CLAIM-TB4-CELL-MIGRATION
“TB-500 supports cell migration”
01
Where it started
The earliest study we have checked that this claim traces back to.
Effects of thymosin β4-derived peptides on migration and invasion of ovarian cancer cells.
Genes Genomics · 2021 · 12 authors · senior author Cha HJ · doi 10.1007/s13258-021-01127-7
“The Tβ4 peptide and all of its derived fragment peptides including those without an actin binding motif stimulate migration and invasion of SKOV3 ovarian cancer cells.” — from the study summary, PubMed ID 34170491
Checked against PubMed on 2026-09-22 · PubMed ↗
02
What was actually tested
Who or what it was tested on, how, what was measured, and the exact words the study used.
- Tested on
- Tested on: not in title
- Test setup
- SKOV3 human ovarian cancer cell line; transwell migration and invasion assays (in vitro)
- What was measured
- Cell migration, invasion, proliferation; RACK-1 expression
- The study’s own words
- “The Tβ4 peptide and all of its derived fragment peptides including those without an actin binding motif stimulate migration and invasion of SKOV3 ovarian cancer cells.”
- Abstract, PMID 34170491
03
How the story spread
From the study, to the retelling, to the people online. Every line says how the two ends are connected. Dashed lines are not confirmed or not connected.
04
How the wording changed
Watch a careful study result turn into a bold post. That is not always lying. But each step is tagged so you can see exactly what changed.
What the study said
The Tβ4 peptide and all of its derived fragment peptides including those without an actin binding motif stimulate migration and invasion of SKOV3 ovarian cancer cells.
05
Studies that back it
Each study we checked, and exactly how it relates to this claim.
Effects of thymosin β4-derived peptides on migration and invasion of ovarian cancer cells.
Genes Genomics · 2021 · 12 authors · senior author Cha HJ · doi 10.1007/s13258-021-01127-7
“The Tβ4 peptide and all of its derived fragment peptides including those without an actin binding motif stimulate migration and invasion of SKOV3 ovarian cancer cells.” — from the study summary, PubMed ID 34170491
Checked against PubMed on 2026-09-22 · PubMed ↗
Effects of BPC-157 and TB-500 on Achilles tendon healing in rats: A histopathological and biomechanical study.
Jt Dis Relat Surg · 2026 · 8 authors · senior author Bayrak BY · doi 10.52312/jdrs.2026.2951
Checked against PubMed on 2026-09-22 · PubMed ↗
Thymosin β4-Enhancing Therapeutic Efficacy of Human Adipose-Derived Stem Cells in Mouse Ischemic Hindlimb Model.
Int J Mol Sci · 2020 · 8 authors · senior author Lim DS · doi 10.3390/ijms21062166
Checked against PubMed on 2026-09-22 · PubMed ↗
Cell starvation increases uptake of extracellular Thymosin β4 and its complexes with calcium.
Int Immunopharmacol · 2023 · 7 authors · senior author Lachowicz JI · doi 10.1016/j.intimp.2023.109743
Checked against PubMed on 2026-09-22 · PubMed ↗
Engineered Tandem Thymosin Peptide Promotes Corneal Wound Healing.
Invest Ophthalmol Vis Sci · 2025 · 6 authors · senior author Gesteira TF · doi 10.1167/iovs.66.14.31
Checked against PubMed on 2026-09-22 · PubMed ↗
06
Studies that push back
Results that found nothing, results that disagree, and criticism of how a study was run.
No study we have checked pushes back on this yet
One study only partly backs it (slightly better scores, but not by enough to count). It is listed above under studies that back it, in its own words. Not finding a study is not the same as proving there is none.
07
What people say
People online describe what they felt. That is worth reading, but it does not prove the product caused it.
YouTube
Not connected yet, so nothing is counted from here
- Posted
- —
- Collected
- —
- First-hand or hearsay
- —
- Original or copy
- —
Not connected yet, so nothing is counted from here
- Posted
- —
- Collected
- —
- First-hand or hearsay
- —
- Original or copy
- —
TikTok
Not connected yet, so nothing is counted from here
- Posted
- —
- Collected
- —
- First-hand or hearsay
- —
- Original or copy
- —
Podcast RSS
Not connected yet, so nothing is counted from here
- Posted
- —
- Collected
- —
- First-hand or hearsay
- —
- Original or copy
- —
08
Copies vs. originals
Ten thousand posts are not ten thousand people. We count how many stories are original and how many are reposts.
Posts found
0
Real-world reports checked: 0 · Time window: none · Platforms connected: none
Original stories
0
Real-world reports checked: 0 · Time window: none · Platforms connected: none
Copies and reposts
0
Real-world reports checked: 0 · Time window: none · Platforms connected: none
Social platforms are not connected yet, so there are no posts to sort into originals and copies.
09
How far it has been tested
From cells in a dish, to animals, to people. The light stops where the checked studies stop.
cell migration
Tested as far as: Cells in a dish — and no further
- Cells in a disha checked study reached this stagereached
- Mouseno checked study has reached this stagestops here
- Ratno checked study has reached this stage
- Bigger animalno checked study has reached this stage
- Peopleno checked study has reached this stage
- Proper human trialno checked study has reached this stage
- Approved by regulatorsno checked study has reached this stage
The full ladder: Cells in a dish → Mouse → Rat → Bigger animal → People → Proper human trial → Approved by regulators
10
The short version
Our plain-English reading. Every sentence comes from a study listed above, or says clearly what we do not have.
- 1The earliest study we have checked measured how human ovarian cancer cells moved in a dish after being treated with thymosin β4 and pieces of it. It is a lab-dish result, not a result in a person.
- 2The first retelling drops the fact that this was cells in a dish. Every version after that adds results the original study never measured.
- 3None of the studies we have checked test this on a real wound in an animal or in people. That means we have not found one, not that one does not exist.
- 4We are not collecting real-world reports yet, so there is nothing from people online to show here.
Written by OnimaChain from the studies on this page only. Those studies: PMID 34170491PMID 42542926PMID 32245208PMID 36706591PMID 41235866
11
What we changed
Every real edit we have made to this claim, with before and after. Nothing gets quietly rewritten.
Claim record created
Before
— (no prior state)
After
tracked
